Previous studies have revealed a critical role for CREB-regulated transcriptional coactivator (CRTC1) in regulating neuronal gene expression during learning and memory.CRTC1 localizes to synapses but undergoes activity-dependent nuclear Handbags translocation to regulate the transcription of CREB target genes.Here we investigate the long-distance r
Programmed cell death (PCD) in plant is triggered by abiotic and biotic stress.Light-dependent PCD is unique to plants.Light-induced PCD also requires reactive oxygen species (ROS) and salicylic acid (SA).In this study, lesion simulating disease1 (LSD1) and elongated hypocotyl 5 (HY5) perform opposite roles to regulate excess red light (RL)-trigger
Protozoan parasites infect and kill millions of people worldwide every year, particularly in developing countries where access to clean fresh water is limited.Among the most common are intestinal parasites, including Giardia lamblia and Entamoeba histolytica.These parasites wreak havoc on the epithelium lining the small intestines (G.lamblia) and c
Three-dimensional (3D) digital brain atlases and high-throughput brain-wide imaging techniques generate large womens hats multidimensional datasets that can be registered to a common reference frame.Generating insights from such datasets depends critically on visualization and interactive data exploration, but this a challenging task.Currently avai